GUGULIPID CAUSES HYPERCHOLESTEROLEMIA LEADING TO ENDOTHELIAL DYSFUNCTION, INCREASED ATHEROSCLEROSIS, AND PREMATURE DEATH BY ISCHEMIC HEART DISEASE IN MALE MICE.

Gugulipid causes hypercholesterolemia leading to endothelial dysfunction, increased atherosclerosis, and premature death by ischemic heart disease in male mice.

For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required.Among the factors that regulate overall cholesterol homeostasis and HDL metabolism, the nuclear farnesoid X receptor plays an important role.Guggulsterone, a bioactive compound presen

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A Fatal A/H5N1 Avian Influenza Virus Infection in a Cat in Poland

A European Shorthair male cat, neutered, approximately 6 years of age, was presented to the veterinary Patio Dining Table clinic due to apathy and anorexia.The cat lived mostly outdoors and was fed raw chicken meat.After 3 days of diagnostic procedures and symptomatic treatment, respiratory distress and neurological signs developed and progressed i

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